Question

Which drug would be most appropriate for providing both long-term asthma control and relief of allergic rhinitis symptoms?

• A. Oral theophylline
• B. Ipratropium bromide inhaler
• C. Salbutamol inhaler
• D. Montelukast

Hint:

Montelukast is useful in both asthma control and allergic rhinitis because it blocks leukotriene action.

Answer 1

The Correct Option is D

Step 1: Understanding the Concept:
Asthma and allergic rhinitis often coexist (the "one-airway" theory). A drug that targets the common inflammatory mediators (leukotrienes) can treat both conditions.
Step 2: Detailed Explanation:
1. Montelukast: It is a Leukotriene Receptor Antagonist (LTRA). Leukotrienes cause bronchoconstriction in the lungs (asthma) and congestion/sneezing in the nose (rhinitis). By blocking their receptors, Montelukast provides dual benefits.
2. Others: Salbutamol and Ipratropium are purely bronchodilators and do not help with rhinitis. Theophylline is an old asthma drug with no benefit for rhinitis.
Step 3: Final Answer:
Montelukast is unique for its ability to manage both maintenance asthma and allergic rhinitis simultaneously.