Topoisomerases are enzymes that modify DNA topology by changing its linking number. They are essential for biological processes such as DNA replication, transcription, and chromosome segregation, where they relieve supercoiling tension by cutting and resealing DNA strands.
| List I | List II |
|---|---|
| (A) Histone erasers | (III) Deacetylases |
| (B) Histone readers | (IV) Bromodomain proteins |
| (C) Histone writers | (I) Methyltransferase |
| (D) DNA unwinding | (II) Topoisomerase |