Question

Match List I with List II

List I		List II
A	α –I antitrypsin	I	Cotton bollworm
B	Cry IAb	II	ADA deficiency
C	Cry IAc	III	Emphysema
D	Enzyme replacement therapy	IV	Corn borer

Choose the correct answer from the options given below:

• A. A-II, B-I, C-IV, D-III
• B. A-III, B-I, C-II, D-IV
• C. A-III, B-IV, C-I, D-II
• D. A-II, B-IV, C-I, D-III

Answer 1

The Correct Option is C

Step 1: Define terms and their functions:

A. $\alpha$-1 antitrypsin:
A protein that inhibits elastase, preventing damage to lung tissue. A deficiency leads to emphysema, characterized by lung tissue breakdown and respiratory difficulties.
Match: A-III (Deficiency causes emphysema).

B. Cry IAb: 
A biopesticide toxin from *Bacillus thuringiensis* (Bt), effective against the cotton bollworm by disrupting its digestive system.
Match: B-IV (Controls Cotton bollworm).

C. Cry IA:c: 
A *Bacillus thuringiensis* (Bt) toxin specifically targeting the corn borer, a pest of maize, by disrupting its digestion.
Match: C-I (Controls Corn borer).

D. Enzyme replacement therapy: 
A treatment for diseases like ADA (Adenosine deaminase) deficiency, which causes severe combined immunodeficiency (SCID). It involves administering the missing enzyme to restore immune function.
Match: D-II (Treats ADA deficiency).

Step 2: Conclusion:

The correct pairings are:

• A - III: $\alpha$-1 antitrypsin deficiency causes emphysema.
• B - IV: Cry IAb controls the Cotton bollworm.
• C - I: Cry IA:c controls the Corn borer.
• D - II: Enzyme replacement therapy treats ADA deficiency.

Answer: The correct answer is (3) A-III, B-IV, C-I, D-II.