Question

A 30-year-old asthmatic patient needs a drug for acute bronchospasm relief. Which agent is most appropriate for rapid bronchodilation?

• A. Inhaled beclomethasone
• B. Inhaled salbutamol (albuterol)
• C. Inhaled ipratropium as monotherapy in a young asthmatic
• D. Oral theophylline

Hint:

For acute asthma attack, remember SABA: Short-Acting Beta Agonist, such as salbutamol, gives rapid bronchodilation.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Asthma management is divided into "controllers" (maintenance) and "relievers" (rescue). Acute bronchospasm requires a drug with a very rapid onset of action to open the airways immediately.
Step 2: Detailed Explanation:
1. Salbutamol (Albuterol): This is a Short-Acting Beta-2 Agonist (SABA). When inhaled, it acts directly on the bronchial smooth muscle receptors, causing relaxation and bronchodilation within 3–5 minutes. This makes it the first-line "rescue" medication.
2. Beclomethasone: This is a corticosteroid. It reduces inflammation over several days or weeks; it has no immediate effect on bronchospasm.
3. Ipratropium: This is an anticholinergic. It is less effective than SABAs in asthma and is generally used as an add-on therapy, not first-line monotherapy for acute relief.
4. Theophylline: This is an oral bronchodilator with a slow onset and many side effects. It is not suitable for emergency use.
Step 3: Final Answer:
Inhaled salbutamol is the drug of choice for rapid relief of acute asthmatic symptoms due to its quick onset of action.