List of top Bioinformatics Questions asked in CUET (PG)

Which feature correctly distinguishes secondary from tertiary structure of protein?

A researcher wants to clone a large DNA fragment \((\sim 40 kb)\) and express it in E. coli. The fragment must replicate autonomously, allow selection of recombinants and come from bacteriophage origin. Which vector is most appropriate?

Which statement best explains why Phosphofructokinase \((PFK-1)\) is considered the major regulatory enzyme of glycolysis?

A bacterial cell exposed to UV radiation shows an increased rate of C-T transitions at specific sites. Later analysis reveals that the same replication fork also accumulated short DNA stretches synthesized by DNA Pol-I. Which DNA repair pathway was most likely activated?

Which of the following statements are correct about imaging and measurement in biology? A. X-ray crystallography determines atomic level structure. B. CT-Scan provides 3D imaging of tissues. C. ECG records brain activity. D. EEG records electrical activity in brain. E. GM Count detects radioactive particles.

Sequence of action of a type II topoisomerase: A. Dissociation of gyrase, B. Translation of unbroken DNA strand, C. Gyrase-DNA complex, D. Ligation, E. Cleavage of DS-DNA.

One of the valid C++ class declaration is:

X-ray crystallography resolution depends primarily on:

Arrange the following memory hierarchy from fastest to slowest: A. RAM, B. SSD, C. HDD, D. Register, E. Cache.

Given below are two statements: Assertion (A): Proteins are made up of alpha amino acids. Reason (R): During denaturation, secondary and tertiary structure of proteins are destroyed.

Match List-I with List-II. List-I: A. Ala amino acid, B. Arg amino acid, C. Asn amino acid, D. Trp amino acid. List-II: I. 6 codons, II. 2 codons, III. 4 codons, IV. 1 codon.

The correct sequence to enter a formula in MS-Excel that contains a built-in function is: A. Type an opening parenthesis \((\). B. Press enter to get result. C. Select an empty cell. D. Select the range of cells and type a closing parenthesis \()\). E. Type an equal sign \((=)\) and then type a function.

Match List-I with List-II. List-I: A. Respiratory disease, B. Tetanus, C. Snake bite, D. Measles. List-II: I. Horse antitoxin, II. Pooled human immune gamma globulin, III. Monoclonal anti-respiratory syncytial virus, IV. Horse antivenin.

Which coenzymes are involved in oxidation-reduction reaction? A. Thiamine pyrophosphate, B. Flavin mononucleotide, C. Flavin adenine dinucleotide, D. Lipoamide, E. Nicotinamide adenine dinucleotide.

Inactivated vaccine is given for protection from following disease: A. Plague, B. Rubella, C. Measles, D. Rabies, E. Mumps.

Which of the following step is not involved in extravasation of both neutrophils and monocytes?

Find the correct sequence of reaction catalyzed by DNA ligase: A. DNA ligase ligates Okazaki fragment to rest of lagging strand. B. Polymerase I eliminates downstream RNA primer by nick translation. C. Unwinding of parental duplex by helicase and elongation of leading strand by polymerase III exposes single-stranded region in front of lagging strand. D. Polymerase III extends DNA Okazaki fragments from primer. E. Primase synthesizes RNA primer.

Given below are two statements: Assertion (A): Hidden Markov Model outperforms simple motif searches for gene prediction. Reason (R): Hidden Markov Model incorporates state transitions and probabilistic modelling.

What is the unit of first order rate constant?

The following virus group has cubic symmetry: A. Tipula Iridescent, B. Canine hepatitis, C. Influenza, D. Vaccinia, E. Polyoma.

Given below are two statements: Assertion (A): C++ is an object-oriented language. Reason (R): C++ supports inheritance, which is an attribute of object-oriented language.

Arrange the following X-ray crystallography workflow sequence: A. Record diffraction images, B. Build atomic model, C. Grow a crystal, D. Mount crystal and expose to X-rays, E. Solve phases and compute electron density.

Match List-I with List-II. List-I: A. Birds, B. Reptiles, C. Sponges, D. Bacteria. List-II: I. 4500 million nucleotide pairs, II. 100 million nucleotide pairs, III. 2 million nucleotide pairs, IV. 2000 million nucleotide pairs.

Find the Laplace transform of \(f(t)=\sin 2t \sin 3t\).

Given below are two statements: Assertion (A): The bond angle in \(NH_3\) is smaller than the bond angle in \(CH_4\). Reason (R): \(NH_3\) contains one lone pair that repels bonding pairs more strongly than a bond pair.