Question:medium

Which statement best explains why Phosphofructokinase \((PFK-1)\) is considered the major regulatory enzyme of glycolysis?

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PFK-1 is the key regulatory enzyme of glycolysis because it catalyzes the committed irreversible step: fructose-6-phosphate to fructose-1,6-bisphosphate.

Updated On: May 18, 2026

It catalyzes only ATP producing step in glycolysis
It controls the first irreversible step that commits glucose to glycolysis
It converts pyruvate into lactate under anaerobic condition
It is the final enzyme of glycolysis and regulates ATP yield

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The Correct Option is B

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