Step 1: Write both slopes
Tangent slope $m$. Perpendicular slope must be $-1/m$.
Step 2: Use points P and (1,0)
Slope from $P(0,y-xm)$ to $(1,0)$ is $-(y-xm)$. Equate to $-1/m$: $m(y-xm)=1$, i.e. $y\,y'-x\,y'^2=1$, option (A).
Final Answer:
Option (A) is the required differential equation.
\[ \boxed{y\,y'-x\,(y')^2=1} \]