Question

The compound that inhibits the growth of tumors is :

• A. cis-$[Pd(Cl)_2(NH_3)_2]$
• B. cis-$[Pt(Cl)_2(NH_3)_2]$
• C. trans-$[Pt(Cl)_2(NH_3)_2]$
• D. trans$-[Pd(Cl)_2(NH_3)_2]$

Answer 1

The Correct Option is B

The question asks which compound inhibits the growth of tumors. To answer this, we need to look at the compounds provided and their known uses in medicine or chemistry.

The options given are:

• cis-[Pd(Cl)_2(NH_3)_2]
• cis-[Pt(Cl)_2(NH_3)_2]
• trans-[Pt(Cl)_2(NH_3)_2]
• trans-[Pd(Cl)_2(NH_3)_2]

The compound cis-[Pt(Cl)_2(NH_3)_2], also known as cisplatin, is well known in the medical community as an antineoplastic agent. It is widely used in chemotherapy to inhibit tumor growth in various types of cancers. It works by binding to and causing crosslinking in DNA, which leads to apoptosis (programmed cell death) in rapidly dividing tumor cells.

Let's evaluate the other options:

• cis-[Pd(Cl)_2(NH_3)_2]: Palladium analogs are not commonly used as chemotherapy drugs.
• trans-[Pt(Cl)_2(NH_3)_2]: Transplatin, the trans isomer of cisplatin, is not effective as a chemotherapy drug. It has a different geometry which does not allow it to bind DNA in the same way that cisplatin does.
• trans-[Pd(Cl)_2(NH_3)_2]: Similar to the cis isomer, the palladium analog in the trans configuration is not used as a chemotherapeutic agent.

Therefore, the compound that inhibits the growth of tumors is cis-[Pt(Cl)_2(NH_3)_2].

In conclusion, the correct answer is cis-[Pt(Cl)_2(NH_3)_2].