Question:medium
Single base difference in ApoE gene is associated with:
Single base difference in ApoE gene is associated with:
Updated On: Jan 14, 2026
- Resistance to HIV (Human Immunodeficiency Virus)
- Migraine
- Huntington disease
- Alzheimer’s disease
Show Solution
The Correct Option is D
Solution and Explanation
Apolipoprotein E, encoded by the ApoE gene, is vital for lipid metabolism. A single nucleotide variation in the ApoE gene, specifically the ApoE4 allele, significantly elevates the risk of Alzheimer's disease.
- Option D: Accurate. The ApoE4 allele heightens vulnerability to Alzheimer's disease.
- Option A, B, C: Inaccurate. These conditions are associated with alternative genes or influences, distinct from the ApoE gene.
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