Question

RNA polymerase responsible for the synthesis of tRNA

• A. RNA Pol 1
• B. RNA Pol 2
• C. RNA Pol 3
• D. RNA Pol 1 and 2

Hint:

A simple mnemonic to remember the eukaryotic RNA polymerases: \textbf{Pol I} \(\rightarrow\) \textbf{r}RNA (most abundant) \textbf{Pol II} \(\rightarrow\) \textbf{m}RNA (most diverse) \textbf{Pol III} \(\rightarrow\) \textbf{t}RNA (and other tiny RNAs) The numbers 1, 2, 3 correspond to the order of the RNA types r, m, t in the word "rampart".

Answer 1

The Correct Option is C

Step 1: Core Idea:
Eukaryotic cells use three RNA polymerases to transcribe different gene types. Step 2: Breakdown:
Each polymerase has a specific role:
RNA Polymerase I (Pol I): Found in the nucleolus, it makes most ribosomal RNAs (rRNAs): 18S, 5.8S, and 28S.
RNA Polymerase II (Pol II): Located in the nucleoplasm, it transcribes protein-coding genes into messenger RNAs (mRNAs). It also synthesizes most small nuclear RNAs (snRNAs) and microRNAs (miRNAs).
RNA Polymerase III (Pol III): Also in the nucleoplasm, it transcribes genes for small, functional RNAs, including all transfer RNAs (tRNAs), 5S ribosomal RNA, and U6 small nuclear RNA.
Step 3: Conclusion:
Transfer RNA (tRNA) synthesis is handled by RNA Polymerase III.