Question

Assertion (A): RNA is unstable and can mutate at a faster rate.
Reason (R): The presence of 2’-OH group in every nucleotide of RNA makes it labile and easily degradable.

• A. Both Assertion (A) and Reason (R) are true and Reason (R) is the correct explanation of the Assertion (A).
• B. Both Assertion (A) and Reason (R) are true, but Reason (R) is not the correct explanation of the Assertion (A).
• C. Assertion (A) is true, but Reason (R) is false.
• D. Assertion (A) is false, but Reason (R) is true.

Hint:

RNA Instability and Mutation Rate

Answer 1

The Correct Option is A

Assertion (A): The 2’-OH group in RNA’s sugar molecule increases its susceptibility to hydrolysis and degradation, rendering it less stable than DNA.
Reason (R): RNA’s inherent reactivity, stemming from its 2’-OH group, leads to greater instability and a higher rate of mutation.