Question:easy
Misoprostol, used in the induction of labour, is an analogue of which type of prostaglandin?
Misoprostol, used in the induction of labour, is an analogue of which type of prostaglandin?
Show Hint
It is the methyl ester analogue, not dinoprostone or carboprost.
Updated On: Jun 23, 2026
- PG E1
- PG E2
- PG I2
- PG F2 alpha
Show Solution
The Correct Option is A
Solution and Explanation
Drug-to-prostaglandin map (memorise this):
Misoprostol = PGE1, dinoprostone = PGE2, carboprost (15-methyl) = PGF2 alpha, epoprostenol = PGI2.
The question asks specifically about misoprostol, so the match is PGE1.
Elimination route: PGI2 is prostacyclin, a pulmonary vasodilator with no oxytocic role, so option c is out. PGF2 alpha analogues are reserved for PPH because they raise smooth-muscle tone strongly, not the first choice for ripening, and that is carboprost not misoprostol, so option d is out. PGE2 is dinoprostone, a different agent, so option b is out. The only correct stem-drug pairing left is PGE1.
Clinical use of misoprostol: cervical ripening, labour induction, medical termination of pregnancy, and management of atonic PPH.
Misoprostol = PGE1, dinoprostone = PGE2, carboprost (15-methyl) = PGF2 alpha, epoprostenol = PGI2.
The question asks specifically about misoprostol, so the match is PGE1.
Elimination route: PGI2 is prostacyclin, a pulmonary vasodilator with no oxytocic role, so option c is out. PGF2 alpha analogues are reserved for PPH because they raise smooth-muscle tone strongly, not the first choice for ripening, and that is carboprost not misoprostol, so option d is out. PGE2 is dinoprostone, a different agent, so option b is out. The only correct stem-drug pairing left is PGE1.
Clinical use of misoprostol: cervical ripening, labour induction, medical termination of pregnancy, and management of atonic PPH.
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