Question

Match List I with List II

List I		List II
A	Down’s syndrome	I	11th chormosome
B	α-Thalassemia	II	‘X’ chromosome
C	β-Thalassemia	III	21st chromosome
D	Klinefelter’s syndrome	IV	16th chromosome

Choose the correct answer from the options given below:

• A. A-I, B-II, C-III, D-IV
• B. A-II, B-III, C-IV, D-I
• C. A-III, B-IV, C-I, D-II
• D. A-IV, B-I, C-II, D-III

Answer 1

The Correct Option is C

This task requires associating genetic disorders with their corresponding chromosomal locations and descriptions. The following linkages are established:

• Down’s syndrome is caused by Trisomy 21. Match: III - 21^st chromosome.
• α-Thalassemia is associated with the 16^th chromosome. Match: IV - 16^th chromosome.
• β-Thalassemia is linked to the 11^th chromosome. Match: I - 11^th chromosome.
• Klinefelter’s syndrome is characterized by an extra 'X' chromosome. Match: II - ‘X’ chromosome.

The resultant pairings are:

A	III
B	IV
C	I
D	II

The definitive solution is: A-III, B-IV, C-I, D-II.