Question

Match List-I with List-II:

Choose the correct answer from the options given below:

• (A) - (III), (B) - (I), (C) - (II), (D) - (IV)
• (A) - (III), (B) - (I), (C) - (IV), (D) - (II)
• (A) - (IV), (B) - (I), (C) - (III), (D) - (II)
• (A) - (III), (B) - (IV), (C) - (I), (D) - (II)

Hint:

To quickly solve mutation matching questions, use clear definitions:
No amino acid change = Silent (I).
Increased/new activity = Gain-of-function (II).
Disturbs wild-type in heterozygote = Dominant negative (IV).

Answer 1

The Correct Option is B