Question

To inhibit the growth of tumours, identify the compounds used from the following:
(A) EDTA
(B) Coordination Compounds of Pt
(C) D – Penicillamine
(D) Cis – Platin
Choose the correct answer from the options given below:

• A. B and D Only
• B. C and D Only
• C. A and B Only
• D. A and C Only

Hint:

Cisplatin and other platinum-based coordination compounds are effective anticancer drugs. They form cross-links with DNA, disrupting cell division and leading to tumour inhibition.

Answer 1

The Correct Option is A

To solve this question, we need to identify which compounds from the given options are known to inhibit the growth of tumors. Let's analyze each compound:

1. EDTA (Ethylenediaminetetraacetic acid):
   • EDTA is primarily used as a chelating agent. It is not known for inhibiting tumor growth. Its main application is in binding metal ions and removing them from solutions or the blood.
2. Coordination Compounds of Pt (Platinum):
   • Many platinum coordination compounds, such as cisplatin, are used in chemotherapy to treat various cancers. These compounds inhibit tumor growth by binding to DNA in cancer cells and preventing their replication.
3. D-Penicillamine:
   • This compound is used primarily in the treatment of Wilson's disease (a disorder of copper metabolism) and rheumatoid arthritis. It does not have applications in inhibiting tumor growth.
4. Cis-Platin (a specific coordination compound of platinum):
   • Cisplatin is a well-known chemotherapeutic agent used extensively in oncology for its effectiveness in treating various types of tumors. It works by cross-linking with DNA and inhibiting cell division.

From the analysis above, the compounds that are used to inhibit tumor growth are Coordination Compounds of Pt and Cis-Platin. Therefore, the correct answer is B and D Only.