Instead of expanding the cross product as a 3 by 3 determinant, we can pull the normalizing factor out first and work with the plain direction vector, then divide by its length at the end. This uses the basic unit vector cross product rules: $\hat{i}\times\hat{i}=\hat{j}\times\hat{j}=\hat{k}\times\hat{k}=0$, $\hat{i}\times\hat{j}=\hat{k}$, $\hat{j}\times\hat{k}=\hat{i}$, $\hat{k}\times\hat{i}=\hat{j}$, and each reversed order flips the sign.
The plain direction vector before normalizing is $\vec{n}_0=\hat{i}+2\hat{j}+\hat{k}$, with length $|\vec{n}_0|=\sqrt{1^2+2^2+1^2}=\sqrt6$, so $\hat{n}=\vec{n}_0/\sqrt6$.
First find $\vec{n}_0\times\vec{B}$ where $\vec{B}=2\hat{i}+2\hat{k}$:
$$ \vec{n}_0\times\vec{B} = (\hat{i}+2\hat{j}+\hat{k})\times(2\hat{i}+2\hat{k}) $$Expand term by term:
$$ = \hat{i}\times2\hat{i} + \hat{i}\times2\hat{k} + 2\hat{j}\times2\hat{i} + 2\hat{j}\times2\hat{k} + \hat{k}\times2\hat{i} + \hat{k}\times2\hat{k} $$Using the rules above, $\hat{i}\times\hat{i}=0$, $\hat{i}\times\hat{k}=-\hat{j}$, $\hat{j}\times\hat{i}=-\hat{k}$, $\hat{j}\times\hat{k}=\hat{i}$, $\hat{k}\times\hat{i}=\hat{j}$, $\hat{k}\times\hat{k}=0$:
$$ = 0 - 2\hat{j} - 4\hat{k} + 4\hat{i} + 2\hat{j} + 0 = 4\hat{i} - 4\hat{k} $$Now divide by $\sqrt6$ to bring back the unit vector, and multiply by the current $I=1$ A to get the force per unit length:
$$ \vec{f} = I(\hat{n}\times\vec{B}) = 1\times\frac{4\hat{i}-4\hat{k}}{\sqrt6} = \frac{4}{\sqrt6}\hat{i} - \frac{4}{\sqrt6}\hat{k}\ \text{N/m} $$Let's summarize: