Question

Which one of the following statements is FALSE regarding vincristine?

• A. It is an alkaloid
• B. Its use is associated with neurotoxicity
• C. It does not cause alopecia
• D. It is a useful drug for induction of remission in acute lymphoblastic leukaemia

Hint:

Pick the wrong claim; vincristine actually does cause hair loss.

Answer 1

The Correct Option is C

Step 1: Read the question as a find the wrong option task. Three statements will be accurate and one will be a misstatement about vincristine.

Step 2: Vincristine is genuinely a vinca alkaloid obtained from a plant, confirming option a. It is also a backbone drug for remission induction in paediatric acute lymphoblastic leukaemia, confirming option d.

Step 3: Neurotoxicity in the form of peripheral neuropathy is the signature dose limiting toxicity of vincristine, so option b is correct as written.

Step 4: That leaves option c, which says alopecia does not occur. Vincristine actually does cause hair loss, so the claim is incorrect, and the false statement is the answer.

\[\boxed{\text{It does not cause alopecia}}\]