Question:medium

Which of the following vaccines is kept at the lowest level? 

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The OPV requires the lowest temperature in the vaccine cold chain, so ensure it is stored at -20°C to -30°C for optimal efficacy.
Updated On: Jun 22, 2026
  • OPV
  • DPT
  • Hep B
  • Rota
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The Correct Option is A

Solution and Explanation

Answer: OPV.

In the vaccine cold chain, different vaccines need different temperatures. The rule that settles this question is simple: a live virus vaccine that must stay frozen is kept the coldest, while most other vaccines only need an ordinary fridge.

Oral Polio Vaccine (OPV) is a live, weakened poliovirus. To keep the virus alive and working, it is stored frozen at about minus 15 to minus 25 degrees Celsius. That is much colder than the rest.

The other three are kept in the normal fridge range of 2 to 8 degrees Celsius:
- DPT must never be frozen, since freezing destroys it.
- Hepatitis B is also fridge-stored and is damaged by freezing.
- Rota vaccine is kept at 2 to 8 degrees Celsius as well.

Since only OPV is stored frozen, it sits at the lowest temperature of the group. So the answer is OPV (option 1).
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