Question:medium

Which of the following vaccines can be used in the clinics?

Show Hint

Do not use vaccines if the VVM has reached discard stage, the vial is expired, frozen when freeze-sensitive, or physically damaged.
Updated On: May 14, 2026
  • Use A only
  • Use A and B
  • Use A, B and C
  • Use D only
Show Solution

The Correct Option is B

Solution and Explanation

Step 1: Understanding the Question:
The question refers to the Vaccine Vial Monitor (VVM), which is a label used to monitor heat exposure of vaccines.
The VVM consists of a square inside a circle. The color change of the inner square relative to the outer circle indicates the usability of the vaccine.
Step 2: Detailed Explanation:

VVM Stages:

Stage A (Usable): The inner square is lighter than the outer circle. This indicates the vaccine has not been exposed to excessive heat.

Stage B (Usable): The inner square is still lighter than the outer circle but has darkened slightly. The vaccine is still potent and can be used.

Discard Point (Stage C): The color of the inner square matches the color of the outer circle. The vaccine must be discarded.

Beyond Discard Point (Stage D): The inner square is darker than the outer circle. The vaccine must be discarded.


Interpretation of the Images: Based on standard VVM diagrams:

Image A shows a light inner square (Usable).

Image B shows a slightly darker but still lighter inner square (Usable).

Images C and D show reached or exceeded discard points (Not usable).


Step 3: Final Answer:
Only vaccines with VVM status A or B are safe for administration in clinical practice.
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