Question:medium
Which of the following lipoproteins does not move towards the charged end in electrophoresis?
Which of the following lipoproteins does not move towards the charged end in electrophoresis?
Show Hint
The biggest, most fat-laden particle stays at the start line.
Updated On: Jun 24, 2026
- VLDL
- LDL
- HDL
- Chylomicrons
Show Solution
The Correct Option is D
Solution and Explanation
Think about how electrophoresis ranks lipoproteins. The separation depends on charge-to-size, and the apoprotein-rich, small $HDL$ particles travel furthest as the alpha band. $VLDL$ lands in the pre-beta zone and $LDL$ in the beta zone, so all three creep toward the anode. Chylomicrons are the giants of the group: enormous, packed with triglyceride, and carrying very little protein per unit size, which leaves them with almost no effective surface charge to drag them through the gel. As a result they are stuck at the origin where the sample was loaded and fail to migrate toward the charged end. The non-migrating particle is therefore the chylomicron.
\[\boxed{\text{Chylomicrons}}\]
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