Question

Which of the following is correct match

• A. Down Syndrome = 21st Chromosome
• B. Sickel cell anaemia = X – Chromosome
• C. Haemophilia = Y – Chromosome
• D. Parkinson Disease = X & Y Chromosome

Answer 1

The Correct Option is A

To determine the correct match for the given question, we need to analyze each of the options with respect to the medical or genetic conditions mentioned:

• Down Syndrome = 21st Chromosome: Down syndrome is a genetic disorder caused by the presence of an extra copy of chromosome 21. This condition is indeed known as Trisomy 21. Therefore, this option is a correct match.
• Sickle Cell Anemia = X-Chromosome: Sickle cell anemia is a genetic disorder caused by a mutation in the hemoglobin-beta gene found on chromosome 11, not the X chromosome. Hence, this option is incorrect.
• Hemophilia = Y-Chromosome: Hemophilia is a bleeding disorder that is typically carried on the X chromosome. It is known as an X-linked recessive disorder, and the incorrect mention of the Y chromosome makes this option wrong.
• Parkinson Disease = X & Y Chromosome: Parkinson's disease is a neurological condition that involves the degeneration of nerve cells. It is not directly linked to specific mutations in the X or Y chromosomes. Therefore, this match is not correct.

Based on the above analysis, the correct answer is: Down Syndrome = 21st Chromosome.