Question

Which of the following drug is alpha 2 agonist?

• A. Apraclonidine
• B. Timolol
• C. PG analogues
• D. Verampamil

Answer 1

The Correct Option is A

Step 1: Sort the four options by drug class. We need the one that stimulates alpha 2 adrenergic receptors.
Step 2: Apraclonidine is a clonidine derivative that selectively activates alpha 2 receptors. In the eye this reduces aqueous humour production and lowers intraocular pressure, which is why it is used in glaucoma.
Step 3: The other choices belong to different classes. Timolol is a beta adrenergic blocker, the prostaglandin analogues act on FP receptors to boost outflow, and verapamil blocks L-type calcium channels.
Step 4: Only apraclonidine matches the alpha 2 agonist description, so it is the answer.
\[\boxed{\text{Apraclonidine}}\]