Step 1: Understanding the Question:
The image (as described by OCR context) shows a white, lacy pattern on the buccal mucosa, consistent with Oral Lichen Planus or a lichenoid reaction. The question asks for the causative drug among the options. Step 2: Detailed Explanation:
Lichenoid Drug Eruptions: These are cutaneous or mucosal reactions that clinically and histologically mimic naturally occurring Lichen Planus. Patients often present with Wickham’s striae (white lacy lines) and a burning sensation.
Lithium Association: Lithium, used in the treatment of bipolar disorder, is a well-documented cause of lichenoid reactions in the mouth. It can also cause or exacerbate skin psoriasis.
Other Causative Drugs: Common culprits for oral lichenoid reactions include NSAIDs, antihypertensives (like ACE inhibitors and Thiazides), and certain anti-malarial drugs. Beta-blockers (Option B) are also linked to these reactions, but Lithium is a very classic and "textbook" association for such mucosal changes in pharmacology exams.
Management: The primary treatment is identifying and discontinuing the offending drug, which usually leads to the resolution of the lesions. Topical steroids may be used for symptom relief if the drug cannot be stopped.
Step 3: Final Answer:
Lithium is a known pharmacological agent capable of inducing lichenoid oral mucosal lesions that cause sensitivity to spicy foods.
