Question:medium

Which is the special stain used for Cryptococcus?

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The stain that colours the polysaccharide capsule wall red identifies this yeast.
Updated On: Jun 23, 2026
  • ZN stain
  • Gram stain
  • Mucicarmine stain
  • Malachite green
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The Correct Option is C

Solution and Explanation

Step 1: Identifying Cryptococcus in tissue relies on demonstrating its carbohydrate-rich capsule and wall.
Step 2: Among special histological stains, mucicarmine binds the polysaccharide of the cryptococcal cell wall and colours it red, giving specific recognition of C. neoformans.
Step 3: The stain is selective because it reacts only with organisms whose wall contains a polysaccharide component, a feature prominent in cryptococcus.
Step 4: Acid-fast (ZN), Gram and spore (malachite green) stains target different structures and are not specific for cryptococcus.
\[\boxed{\text{Mucicarmine stain}}\]
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