Question

Which is the best investigation for carcinoma head of pancreas:

• A. Guided biopsy
• B. ERCP
• C. Transduodenal/transperitoneal sampling
• D. EUS

Answer 1

The Correct Option is D

Step 1: The decisive investigation for a suspected pancreatic head cancer is the one that yields tissue for a histological diagnosis.
Step 2: A percutaneous needle biopsy directed by ultrasound or CT can sample the lesion and establish the diagnosis directly.
Step 3: It must be done cautiously because these tumours have a rich blood supply and the procedure carries a risk of bleeding.
Step 4: Compared with ERCP, transduodenal sampling and EUS, the guided biopsy is the option that gives the confirmatory tissue, so it is the best investigation here.
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