Question

What is the most common karyotype seen in true hermaphroditism (ovotesticular disorder of sex development)?

• A. 45 X0 with streak gonads
• B. 46 XX with ovotestis
• C. 47 XY +9
• D. 47 XX

Hint:

Recall the gonad named ovotestis and its usual chromosome count.

Answer 1

The Correct Option is B

Mnemonic-led answer: True hermaphrodite carries the ovotestis, the gonad that holds both ovarian and testicular tissue. Tie that picture to its commonest chromosome pattern, 46 XX, which appears in roughly 9 out of 10 cases.

Ruling out the distractors: 45 X0 with streak gonads is the signature of Turner syndrome, a girl with short stature and gonadal dysgenesis, not mixed gonadal tissue. 47 XY +9 is a trisomy aneuploidy unrelated to sex reversal. 47 XX is not a recognised karyotype for this disorder.

So: the option that pairs the ovotestis with 46 XX is the correct one, matching the 90% figure quoted in the literature.