Question

The process of separation of a racemic modification into d and l-enantiomers is called

• A. resolution
• B. dehydration
• C. revolution
• D. dehydrohalogenation

Answer 1

The Correct Option is A

The question pertains to a fundamental concept in stereochemistry, which is the branch of chemistry dealing with the spatial arrangement of atoms in molecules. The correct answer is resolution.

Let's go through the reason why "resolution" is the correct answer:

1. Racemic Mixture: A racemic mixture or racemate is an equimolar mixture of two enantiomers, which are molecules that are mirror images of each other but cannot be superimposed. These enantiomers are labeled as D (dextrorotatory) and L (levorotatory) based on their effect on plane-polarized light.
2. Resolution Process: The process of separating these two optically active enantiomers from their racemic mixture is called resolution. This can be achieved by various methods such as crystallization, chiral chromatography, or enzymatic separation where one enantiomer is converted into a derivative with a chiral reagent.
3. Other Options:
   • Dehydration: This is a chemical reaction involving the removal of a water molecule from a compound, usually not related to enantiomer separation.
   • Revolution: This refers to a circular motion around an axis, which is not applicable in chemistry for separating enantiomers.
   • Dehydrohalogenation: A chemical reaction that involves the removal of a hydrogen halide from a substrate molecule, again unrelated to the resolution of enantiomers.

Therefore, in stereochemistry, the specific process of separating a racemic modification into D and L enantiomers is called resolution.