Update both prices first, then compute company B's two revenues and subtract. The 2022 prices become $320+20=340$ for Fertilizer-P and $280+20=300$ for Fertilizer-Q. Company B's Fertilizer-P quantity is $0.22\times12000=2640$ Kg, giving revenue $2640\times340=897600$. Company B's Fertilizer-Q quantity is $0.21\times15000=3150$ Kg, giving revenue $3150\times300=945000$. The difference between the two revenues is $945000-897600=47400$. \[\boxed{Rs\ 47400}\]