Question

The Cri-du-chat syndrome, a chromosomal aberration occurs in humans due to ...........

• A. Duplication
• B. Inversion
• C. Deletion
• D. Translocation

Hint:

Cri-du-chat syndrome is caused by a deletion in chromosome 5, leading to developmental issues and distinct physical features.

Answer 1

The Correct Option is C

Step 1: Cri-du-chat Syndrome Explained.
Cri-du-chat syndrome results from a deletion on the short arm of chromosome 5. The syndrome's name originates from the distinctive cat-like cry of affected infants.
Step 2: Evaluating Options.
- Duplication: A repeated chromosome segment. This does not cause Cri-du-chat syndrome.
- Inversion: A reversed chromosome segment. This is also not the cause.
- Deletion: The accurate cause, involving the loss of a segment from chromosome 5.
- Translocation: The transfer of a chromosome segment to another. This does not lead to Cri-du-chat syndrome.
Step 3: Final Determination.
Option (3) Deletion is the correct answer.
Final Answer: \[\boxed{\text{The correct answer is (3) Deletion.}}\]