Question

The chirality of the compound

• A. R
• B. S
• C. Z
• D. E

Answer 1

The Correct Option is A

To determine the chirality of the compound shown in the image, we use the Cahn-Ingold-Prelog (CIP) priority rules to assign the absolute configuration as either R or S.

1. Identify the four substituents attached to the chiral center and assign priorities based on atomic number. The substituents are:
   • Bromine (Br) - Atomic number 35
   • Chlorine (Cl) - Atomic number 17
   • Methyl group (CH₃) - Carbon has atomic number 6
   • Hydrogen (H) - Atomic number 1
2. Assign priorities:
   • Priority 1: Bromine (Br)
   • Priority 2: Chlorine (Cl)
   • Priority 3: Methyl group (CH₃)
   • Priority 4: Hydrogen (H)
3. Orient the molecule so that the group with the lowest priority (Hydrogen) is pointing away from you.
4. Observe the sequence of groups 1, 2, and 3. If the sequence is clockwise, the configuration is R. If it is counterclockwise, the configuration is S.
5. In this compound, moving from Br (1) to Cl (2) to CH₃ (3) is clockwise. Therefore, the configuration is R.

Thus, the absolute configuration of the chiral carbon in the compound is R.