Question:easy
Niacin therapy is relatively contraindicated in diabetes because it:
Niacin therapy is relatively contraindicated in diabetes because it:
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Niacin worsens glucose tolerance and insulin resistance.
Updated On: Jun 24, 2026
- Increases the blood sugar levels
- Causes scleroderma
- Is difficult to give by injection
- Increases the metabolism of oral hypoglycemic drugs
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The Correct Option is A
Solution and Explanation
Step 1: Niacin is used to lower LDL and triglycerides and to raise HDL, but it has an unwanted action on carbohydrate handling.
Step 2: It promotes insulin resistance and reduces glucose tolerance, which pushes fasting and post-meal glucose upward.
Step 3: In someone who already has diabetes, this hyperglycemic effect can destabilize control, so niacin is used cautiously or avoided.
Step 4: The cause therefore is its tendency to raise blood glucose, not scleroderma, injection issues, or drug metabolism changes.
\[\boxed{\text{It increases blood sugar levels}}\]
Step 2: It promotes insulin resistance and reduces glucose tolerance, which pushes fasting and post-meal glucose upward.
Step 3: In someone who already has diabetes, this hyperglycemic effect can destabilize control, so niacin is used cautiously or avoided.
Step 4: The cause therefore is its tendency to raise blood glucose, not scleroderma, injection issues, or drug metabolism changes.
\[\boxed{\text{It increases blood sugar levels}}\]
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