Step 1: Anchor on two well known industrial fermentations.
Butyric acid is produced by anaerobic fermentation using Clostridium, and citric acid is produced commercially through Aspergillus niger fermentation.
Step 2: Filter the options with these two facts.
Keep only the option where the butyric acid item pairs with Clostridium and the citric acid item pairs with Aspergillus.
Step 3: Confirm the remaining two.
Cyclosporin-A is sourced from a fungus used in immunosuppressant drug production, and the last item completes the set by elimination.
Final answer: Option 3, A-IV, B-III, C-II, D-I.