Question

Match the enzyme with its function. 

 

• A. A-2, B-1, C-3, D-4
• B. A-3, B-2, C-4, D-1
• C. A-2, B-3, C-1, D-4
• D. A-4, B-1, C-2, D-3

Hint:

Think of the replication fork as a zipper: Helicase is the slider unzipping it, Topoisomerase untangles the threads ahead, Pol I removes the starting marks, and Ligase glues the final pieces together.

Answer 1

The Correct Option is A

To match the enzymes with their respective functions, we need to understand the role of each enzyme in DNA replication and repair processes.

1. DNA ligase: This enzyme is responsible for joining DNA fragments, particularly during the lagging strand synthesis where it joins Okazaki fragments. Therefore, it matches with 2. Joins DNA fragments.
2. DNA polymerase I: This enzyme is involved in the removal of RNA primers and replacing them with DNA. Therefore, it matches with 1. Removes RNA primers.
3. Helicase: Helicase unwinds the DNA double helix at the replication fork to allow the replication machinery access to the DNA template strands. Therefore, it matches with 3. Unwinds DNA.
4. Topoisomerase: This enzyme relieves the supercoiling tension that builds up ahead of the replication fork due to unwinding. Therefore, it matches with 4. Relieves supercoiling.

Based on these functions, the correct match is:

A-2, B-1, C-3, D-4

Hence, the correct answer is A-2, B-1, C-3, D-4.