Question

Match List-I with List-II

List-I (Particulars) & List-II (Nomenclature)
(A) An increase in the size of the triplet repeat & (I) Frameshift mutation
(B) A 5 bp deletion in an exon & (II) Transversion
(C) Substitution of one amino acid for another & (III) Expansion
(D) An A to a T point mutation & (IV) Missense mutation

• (A) - (II), (B) - (I), (C) - (III), (D) - (IV)
• (A) - (III), (B) - (II), (C) - (IV), (D) - (I)
• (A) - (IV), (B) - (I), (C) - (II), (D) - (III)
• (A) - (III), (B) - (I), (C) - (IV), (D) - (II)

Hint:

To solve mutation matching questions quickly:
- Transition = Purine to Purine (A $\leftrightarrow$ G) or Pyrimidine to Pyrimidine (C $\leftrightarrow$ T).
- Transversion = Purine to Pyrimidine (A/G $\leftrightarrow$ C/T).
- Deletions/Insertions not divisible by 3 = Frameshift.

Answer 1

The Correct Option is D