Question

Match List-I with List-II 

Choose the correct answer from the options given below: 
 

• (A) - (I), (B) - (II), (C) - (III), (D) - (IV)
• (A) - (I), (B) - (III), (C) - (II), (D) - (IV)
• (A) - (I), (B) - (II), (C) - (IV), (D) - (III)
• (A) - (III), (B) - (IV), (C) - (I), (D) - (II)

Hint:

Associate major bioinformatics organizations with their flagship tools and databases: \textbf{NCBI} (USA): GenBank, PubMed, BLAST, \textbf{Cn3D}. \textbf{ExPASy}/SIB (Swiss): Swiss-Prot, \textbf{DeepView} (Swiss-PdbViewer). \textbf{EBI} (Europe): EMBL-Bank, InterPro, \textbf{PROCHECK}. \textbf{PDB} (Worldwide): The global archive for 3D structural data of biological macromolecules.

Answer 1

The Correct Option is A

Step 1: Overview:
This question tests your ability to link bioinformatics software to their origin (source, developer, or related database/portal). These tools are used for molecular visualization and structural analysis.
Step 2: Detailed Breakdown:
(B) Cn3D: This 3D molecular structure viewer is from the NCBI (National Center for Biotechnology Information) and integrates well with NCBI resources. Thus, (B) matches (II).
(C) DeepView (Swiss-PdbViewer): A popular protein visualization and analysis tool developed at the Swiss Institute of Bioinformatics (SIB), it's associated with the ExPASy (Expert Protein Analysis System) proteomics server. Thus, (C) matches (III).
(D) PROCHECK: This program assesses protein structure quality (e.g., Ramachandran plots). Developed by Roman Laskowski et al., major versions are distributed through resources at the EBI (European Bioinformatics Institute). Thus, (D) matches (IV).
(A) WebMol: This molecular viewer displays structures from the PDB (Protein Data Bank). WebMol is directly linked to viewing PDB data. Considering the other matches, this is the logical association. Thus, (A) matches (I).
Step 3: Solution:
The correct matches are: (A)-(I), (B)-(II), (C)-(III), (D)-(IV). This aligns with option (1).