If lines represented by the equation $px^2 - qy^2 = 0$ are distinct, then
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We can rewrite the equation as $px^2 = qy^2 \implies \frac{y^2}{x^2} = \frac{p}{q} \implies \frac{y}{x} = \pm\sqrt{\frac{p}{q}}$. For these lines to be real and distinct, the value under the square root must be strictly positive, meaning $\frac{p}{q} \gt 0$, which is algebraically equivalent to $pq \gt 0$!