Step 1: Recall how direction ratios of a join are found.
The direction ratios of the line joining two points are the differences of their coordinates.
Step 2: Subtract the coordinates.
For $A(4,3,-5)$ and $B(-2,1,-8)$, we get $a=-2-4=-6$, $b=1-3=-2$, $c=-8-(-5)=-3$.
Step 3: Build the point $P$.
The point is $P(a,3b,2c)=(-6,\,3(-2),\,2(-3))=(-6,-6,-6)$.
Step 4: Test the candidate planes by substitution.
A point lies on a plane when its coordinates satisfy the plane equation. We substitute $(-6,-6,-6)$.
Step 5: Check $x+y-2z=0$.
$-6+(-6)-2(-6)=-12+12=0$, which is satisfied. The other options give nonzero values, for example $x+y+z=-18\neq0$.
Step 6: Conclude.
So $P$ lies on the plane $x+y-2z=0$.
\[ \boxed{x+y-2z=0} \]