Question:hard

If 2 g of benzoic acid is dissolved in 25 g of benzene, its depression in freezing point was found to be 1.62 K. Molal depression constant of benzene is 4.9 K kg mol-1. If benzoic acid forms a dimer in this solution, what will be the percentage association of benzoic acid? (5)
OR
A 200 cm3 aqueous solution of a protein contains 1.26 g of protein. The osmotic pressure of this solution at 300 K is \(2.57\times10^{-3}\) bar. Calculate the molar mass of this protein. (5)

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Option 1: find the van't Hoff factor i from \(\Delta T_f = iK_f m\), then use \(i = 1 - \alpha/2\) for dimerisation. Option 2: use \(M = wRT/\pi V\) with R = 0.083 L bar K-1mol-1.
Updated On: Jul 10, 2026
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Solution and Explanation

Option 1 (Benzoic acid dimer) — observed molar mass route:
Step 1: Association changes the effective particle count, so first find the experimental (observed) molar mass from the depression data using \(M_{obs} = \dfrac{K_f \times w_2 \times 1000}{\Delta T_f \times w_1}\), where \(w_2\) is solute mass and \(w_1\) is solvent mass in grams.
Step 2: \(M_{obs} = \dfrac{4.9 \times 2 \times 1000}{1.62 \times 25} = \dfrac{9800}{40.5} = 241.98\) g mol\(^{-1}\).
Step 3: The van't Hoff factor is the ratio of the true molar mass to the observed molar mass: \(i = \dfrac{M_{normal}}{M_{obs}} = \dfrac{122}{241.98} = 0.504\).
Step 4: Because two molecules combine into one dimer, \(i = 1 - \dfrac{\alpha}{2}\), giving \(\alpha = 2(1 - 0.504) = 0.992\).
Step 5: \[\boxed{\text{Percentage association} = 99.2\%}\] The observed molar mass being nearly double 122 confirms almost complete dimerisation.

Option 2 (Protein) — moles-of-particles route:
Step 1: First find the number of moles of protein directly from \(n = \dfrac{\pi V}{RT}\).
Step 2: \(n = \dfrac{(2.57\times10^{-3}\text{ bar})(0.200\text{ L})}{(0.083\text{ L bar K}^{-1}\text{mol}^{-1})(300\text{ K})} = \dfrac{5.14\times10^{-4}}{24.9} = 2.064\times10^{-5}\) mol.
Step 3: Molar mass is total mass divided by moles: \(M = \dfrac{w}{n} = \dfrac{1.26}{2.064\times10^{-5}}\).
Step 4: \[\boxed{M \approx 61039\text{ g mol}^{-1}}\] a large value typical of macromolecules such as proteins.
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