Question

Identify ``X'' name of enzyme; and ``Y'' enzyme class number by observing the reaction given below:
\[ \text{Glutamic acid} + NH_3 + \text{ATP} \xrightarrow{X} \text{Glutamine} + \text{ADP} + \text{iP} \]

• A. X - Glutamine oxidase, Y - 2
• B. X - Glutamine synthetase, Y - 6
• C. X - Glutamine reductase, Y - 4
• D. X - Glutamine carboxylase, Y - 5

Hint:

Use the mnemonic {OTH LIL} to remember enzyme classes: Oxidoreductases, Transferases, Hydrolases, Lyases, Isomerases, Ligases.

Answer 1

The Correct Option is B

Step 1: Understanding the Reaction:
The reaction shows the conversion of Glutamic acid to Glutamine by the addition of ammonia ($NH_3$), utilizing energy from ATP hydrolysis ($ATP \rightarrow ADP + iP$).
Step 2: Identifying Enzyme X:
Enzymes that catalyze the joining of two molecules coupled with the breakdown of a pyrophosphate bond in ATP are called Synthetases (or Ligases). Specifically, the enzyme converting Glutamate to Glutamine is Glutamine synthetase.
Step 3: Identifying Enzyme Class Y:
According to the International Union of Biochemistry and Molecular Biology (IUBMB), enzymes are classified into 6 main classes:
Oxidoreductases
Transferases
Hydrolases
Lyases
Isomerases
Ligases (Synthetases)
Since this enzyme joins two molecules using ATP, it belongs to the class **Ligases**, which is **Class 6**.
Step 4: Final Conclusion:
X is Glutamine synthetase, and Y is Class 6.