Question

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Intracellular receptors that act as transcription factors become activated by physiological ligands. Reason (R): They are activated in the interior of the cell (unlike extracellular receptors) because their physiological ligands are lipophilic in nature. In the light of the above statements, choose the most appropriate answer from the options given below:

• A. Both (A) and (R) are correct and (R) is the correct explanation of (A) \
• B. Both (A) and (R) are correct but (R) is not the correct explanation of (A) \
• C. (A) is correct but (R) is not correct \
• D. (A) is not correct but (R) is correct

Hint:

Lipophilic molecules (like steroids) pass through cell membranes like ghosts. They go straight inside to find their intracellular receptors.

Answer 1

The Correct Option is A