Question

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R). Assertion (A): Protein synthesis is a central function in cellular physiology and is the primary target of many naturally occurring antibiotics and toxins. Tetracyclines are a class of broad-spectrum antibiotics used in the management and treatment of infectious disease by inhibiting translational machinery in bacteria. Reason (R): Tetracyclines inhibit protein synthesis in bacteria by blocking the A site on the ribosome, preventing the binding of aminoacyl tRNA. In the light of the above statements, choose the most appropriate answer from the options given below:

• A. Both (A) and (R) are correct and (R) is the correct explanation of (A) \
• B. Both (A) and (R) are correct but (R) is not the correct explanation of (A) \
• C. (A) is correct but (R) is not correct \
• D. (A) is not correct but (R) is correct

Hint:

Tetracycline blocks the A site, stopping the entry of Aminoacyl-tRNA. Without new amino acids, bacterial protein synthesis grinds to a halt.

Answer 1

The Correct Option is A