Question

Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R).

Assertion (A): In a zinc finger about 30 amino acids form an elongated loop held together at the base by a single \(\text{Zn}^{2+}\) ion which is coordinated to form residues (with Cys and/or His).

Reason (R): The Zn does not itself interact with DNA, rather the coordination of Zn with amino acid residues stabilizes the small structural motif.

In the light of the above statements, choose the most appropriate answer from the options given below:

• A. Both (A) and (R) are correct and (R) is the correct explanation of (A) \
• B. Both (A) and (R) are correct but (R) is not the correct explanation of (A) \
• C. (A) is correct but (R) is not correct \
• D. (A) is not correct but (R) is correct

Hint:

Zinc acts purely as a structural anchor or "glue" for the loop. The protein framework does the actual work of recognizing and binding the DNA sequence.

Answer 1

The Correct Option is B