Another way to settle this is to think about the typical materials each of these dryers is used for in practice, and see which use-case matches "heat-sensitive."
- Tray dryer: Commonly used for granules and bulk drugs that can tolerate moderate heat over an extended drying time - not the go-to choice for delicate, heat-labile materials.
- Vacuum dryer: Commonly used specifically for thermolabile drugs, natural extracts, and enzymes where high temperature would degrade the active material - this matches the scenario in the question directly.
- Tunnel dryer: Typically used for continuous, large-scale drying of bulkier or more heat-tolerant materials moving on a conveyor.
- Drum dryer: Typically used for viscous liquids or slurries such as milk powder or starch, where intense direct heat is acceptable or even needed.
Only one of these use-cases is built around protecting heat-sensitive material.
Hence, the correct answer is Vacuum dryer.