Question

Avicel pH 102 is available in this particular form

• A. Powder form
• B. Granular form
• C. Semisolid form
• D. Liquid crystalline state

Hint:

Microcrystalline cellulose (MCC) like Avicel pH 102 is commonly used in tablet formulations and is typically available in powder form.

Answer 1

The Correct Option is A

Avicel pH 102 is a microcrystalline cellulose excipient commonly used as a diluent and binder in direct-compression tablet formulations. As referenced in this question, it is supplied and used in powder form, which allows it to be blended directly with active ingredients and other excipients before compression. The other listed physical forms (granular, semisolid, liquid crystalline) do not describe how this excipient is characterized here.

Therefore, the correct answer is Powder form.

Answer 2

Another way to confirm this is to think about what physical form would actually be practical for each option in a tablet-manufacturing context.

1. Powder form: A dry powder can be easily metered, blended with other excipients, and compressed directly into tablets, which is consistent with how Avicel pH 102 is used in this question.
2. Granular form: Although granulation is a separate processing step used with many excipients, it is not the form specified for Avicel pH 102 in this question.
3. Semisolid form: A semisolid material could not be compressed into a solid tablet in the conventional sense, ruling this out for a tableting excipient.
4. Liquid crystalline state: This ordered-liquid phase is not compatible with the solid-dosage manufacturing process that Avicel pH 102 is used for.

Only a dry powder form is practical and consistent with how Avicel pH 102 is used in tablet manufacturing, as described in this question.

Therefore, the correct answer is Powder form.