Question:medium

During which phase of the cell cycle are chromosomes most condensed and visible under a microscope?

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To perform karyotyping or prepare chromosome spreads, researchers treat dividing cells with colchicine.
This chemical disrupts spindle fibers, arresting mitosis at metaphase (within the M phase) when chromosomes are at their maximum level of condensation.
Updated On: Jul 13, 2026
  • G1 phase
  • S phase
  • G2 phase
  • M phase (mitosis)
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The Correct Option is D

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