Question

Coenzyme A serves as a carrier of activated acetyl or acyl group. Key enzymes involving Coenzyme A are:
A. Pyruvate dehydrogese
B. $\alpha$- Ketoglutarate dehydrogese
C. Thiokise
D. Glyceraldehyde 3 phosphate dehydrogese

• A. B, C and D Only
• B. A, C and D Only
• C. A, B and C Only
• D. A, B and D Only

Hint:

Coenzyme A (CoA-SH) participates in thioester bond formation:
1. Pyruvate Dehydrogese $\to$ Forms Acetyl-CoA.
2. $\alpha$-Ketoglutarate Dehydrogese $\to$ Forms Succinyl-CoA.
3. Thiokise $\to$ Forms Acyl-CoA Succinyl-CoA.
GAPDH uses inorganic phosphate ($\text{P}_i$), NOT Coenzyme A!

Answer 1

The Correct Option is C