Step 1: Define "Speedball". "Speedball" describes a combined stimulant and depressant, often an opioid, ingested together, often by injection. The question title "CNS depressant Speed balls" is imprecise; a speedball includes both a depressant and a stimulant.
Step 2: Identify the classic combination. The typical speedball blends heroin (an opioid depressant) with cocaine (a potent stimulant).
Step 3: Evaluate the options. Option (3) accurately reflects this combination. The remaining choices are incorrect.