To determine the answer to the question "Calamine is an ore of:", we need to understand what ore is and identify the metal associated with Calamine.
Definition of Ore: An ore is a natural occurring solid material from which a metal or valuable mineral can be profitably extracted.
Explanation: Calamine is a mineral that is primarily composed of zinc carbonate (ZnCO3). This makes it an important ore for the metal zinc.
Based on the above analysis, Calamine is primarily associated with zinc.
Hence, the correct answer is: Zinc.