Question

Basiliximab is an

• A. IL-1 receptor antagonist
• B. Anti-CD3 antibody
• C. IL-2 receptor antagonist
• D. TNF inhibitor

Answer 1

The Correct Option is C

Step 1: Basiliximab is an anti-CD25 monoclonal antibody, CD25 being the alpha subunit of the IL-2 receptor found on activated T-cells.

Step 2: Because it clamps onto this receptor subunit with high affinity, it stops interleukin-2 from triggering the T-cell, so functionally it behaves as an IL-2 receptor antagonist.

Step 3: Clinically it guards transplanted organs against rejection, clears in roughly a week, and may provoke anaphylaxis or infections. The remaining labels - IL-1 antagonist, anti-CD3 and TNF inhibitor - describe other drugs, leaving the IL-2 receptor antagonist as the answer.

\[\boxed{\text{IL-2 receptor antagonist}}\]