Question:medium
All are true about Parvovirus except:
All are true about Parvovirus except:
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Vertical transmission of B19 in pregnancy is much higher than 10%.
Updated On: Jun 24, 2026
- < 10% spread by transplacental route
- Spread by respiratory route
- It is a DNA virus
- Affects erythroid progenitor cells
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The Correct Option is A
Solution and Explanation
Parvovirus B19 is the smallest DNA virus that infects humans, built from a single strand of DNA with no envelope, which makes option C accurate. The usual route of person-to-person transmission is inhalation of respiratory droplets, confirming option B, with additional spread via blood products and across the placenta. The hallmark of the virus is its tropism for dividing erythroid precursors, which it reaches through the P blood-group antigen; the resulting halt in red cell production explains aplastic crises and validates option D. The statement that does not hold is the figure for vertical transmission. Maternal infection in pregnancy carries a meaningful risk of crossing to the fetus, with transmission rates classically cited near 30%, far above the under-10% value given. Severe fetal anaemia and hydrops fetalis can follow. Hence the low transplacental figure is the false option.
\[\boxed{< 10\% \text{ spread by transplacental route}}\]
\[\boxed{< 10\% \text{ spread by transplacental route}}\]
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